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Alpha Glucosylrutin

Alpha Glucosylrutin is a powerful, naturally derived antioxidant and photoprotective ingredient used in cosmetics for its ability to neutralize free radicals, protect against sun-induced damage, and prevent sun allergies. Alpha Glucosylrutin is particularly beneficial in after-sun and sunscreen products, as well as in anti-aging and skin-whitening formulations, due to its improved water solubility, stability, and epidermal bioavailability compared to its parent compound, rutin.

  • Product Name: Alpha Glucosylrutin
  • INCI Name: Alpha Glucosylrutin
  • Synonyms: Glucosylrutin, Alpha-glucosylrutin, α-Glucosylrutin 4G-alpha-D-glucopyranosyl-rutin
  • CAS No.: 130603-71-3
  • Funtions: Antioxidant,Brightening and lightening,Anti-inflammatory and soothing

Alpha Glucosylrutin, also known as Alpha-Glucosyl Rutin (α-glucosyl rutin) or Alpha-Glucosylrutin (AGR), is a derivative of the natural flavonoid compound rutin. It is produced through biotechnological methods by attaching one molecule of glucose to rutin via an α-glycosidic bond. This method has mild conditions and high specificity. This structural modification significantly improves rutin's poor water solubility, instability, and difficulty in skin absorption, making it an efficient, stable, and easily applicable top-tier cosmetic ingredient.

 

Rutin, also known as rutin, vitamin P is mostly derived from rutin leaves, tobacco leaves, dates, apricots, orange peels, tomatoes, buckwheat flowers, etc. It has excellent antioxidant, anti-allergic and stable pigment capabilities, but its solubility is low and its application range is limited. Alpha-Glucosyl Rutin is 12,000 times water-soluble than rutin. Alpha-Glucosyl Rutin is freed by the action of enzymes in the organism. Alpha-Glucosyl Rutin is widely used in cosmetics and other fields. Alpha-Glucosyl Rutin has very good antioxidant and ultraviolet absorption effects, and can resist skin photoaging, delay aging and resist blue light.

 

Alpha-Glucosylrutin (AGR) has exceptional water solubility which is the most critical advantage Alpha-Glucosylrutin. Ordinary Rutin is almost insoluble in water, greatly limiting its application in cosmetics. The introduction of hydrophilic glucose groups significantly enhances its water solubility (up to >500g/L), making it easy to apply in various aqueous formulations, serums, and emulsions.

 

Alpha-Glucosylrutin (AGR) has extremely high stability. Ordinary Rutin is sensitive to light and heat, easily decomposing and becoming ineffective. The introduction of glucose groups acts like an 'umbrella', enhancing the molecular structure's stability, ensuring high activity throughout the formulation process and product shelf life, with better tolerance to UV light and heat environments.

 

Alpha-Glucosylrutin (AGR) has excellent skin absorption and bioavailability. Although the molecular weight increases after glycosylation, the balance between lipophilicity and hydrophilicity improves, and it may release active forms through glycosidase action on the skin, thus more easily penetrating the stratum corneum and being effectively utilized by the skin, with bioavailability far exceeding that of ordinary rutin.

alpha glucosylrutin skin brightening

Key Technical Parameters:

Appearance Yellow powder
Identification A brown color develops
Rutin 20%
Monoglucosyl Rutin 79%
Clarity and Color in Solution Clear
Heavy metal(As Pb) ≤10ppm
Loss on drying ≤8.0%
Residue on ignition ≤0.5%
Aerobic plate count ≤100 cfu/g
Yeast and mold ≤100 cfu/g
Coliforms Negative

 

Functions:

Antioxidant

* UV protection

* Protect collagen

* Prevent pigment fading

* Brightening and lightening

* Anti-inflammatory and soothing

* Prevent spice deterioration

Applications:

* Sun protection products: Added as a key active ingredient to sunscreen, day cream, and primer to enhance light protection effects;

* Whitening and spot-removing essence: Used as a core whitening ingredient to brighten skin tone and fade spots;
*Anti-aging products: Used in essences and face creams to combat free radicals and delay skin aging;
*Soothing and repairing products: Used in skin care products for sensitive or damaged skin.

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