Crospovidone
Pharmaceutical Excipient Crospovidone is a crosslinked PVP,insoluble PVP,it is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.
Key Technical Parameters:
| Product | Crospovidone Type A | Crospovidone Type B |
| Appearance | White or yellowish-white powder or flakes | |
| Identifications | A.Infrared Absorption | |
| B.No blue color develops. | ||
| C.A Suspension is formed and no clear solution is obtained within 15 min. | ||
| D.Majority of particles are in the range 50 ~300 μm is type A,majority of particles are in the range 5~50 μm | ||
| Solubility | Practically insoluble in water,in alcohol and in methylene chloride | |
| Water- soluble substances | 1.0% max | 1.0% max |
| pH((1% in water) | 5.0 –8.0 | 5.0 –8.0 |
| Loss on Drying | 5.0% max. | 5.0% max. |
| Sulphated Ash | 0.1% max. | 0.1% max. |
| Nitrogen content | 11.0 -12.8 % | 11.0 -12.8 % |
| Impurity A | 10 ppm max. | 10 ppm max. |
| Peroxide(As H2O2) | 400 ppm max. | 1000 ppm max. |
| Heavy Metals | 10 ppm max. | 10 ppm max. |
Applications:
Crospovidone are widely used as 1)Disintergrating agent,2)Stabilizer for suspension,3)Moisture Absorbent, 4)Complextant of Polyphenols and Tannin for the extract formulations.
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Food Grade PVPP is a crosslinked PVP,insoluble,it is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.
Key Technical Parameters:
| Product | PVPP (One Way) | PVPP(Regenerate) |
| Appearance | White to off-white,hygroscopic,free-flowing powder | |
| Solubility | Insoluble in water and other common solvents. | |
| Odour of the suspension | Faint,Typical | |
| Nitrogen | 11.0-12.8% | 11.0-12.8% |
| Heavy metals(As Pb) | 10ppm max. | 10ppm max. |
| Lead | 2 ppm max. | 2 ppm max. |
| Arsenic | 2 ppm max. | 2 ppm max. |
| pH(1% in Water Suspension) | 5.0-8.0 | 5.0-8.0 |
| Sulphated Ash | 0.4% max. | 0.4% max. |
| Water soluble substances | 0.5% max. | 0.5% max. |
| Solubility in Acetic Acid/Ethnol | 1.0% max. | 1.0% max. |
| Peroxides | 400 ppm max. | 400 ppm max. |
| N,N-Divinylimidazolidione | 2ppm max. | 2ppm max. |
| N-Vinylpyrrolidone | 10 ppm max. | 10 ppm max. |
| Water | 5.0% max. | 5.0% max. |
| Paticle Size | / | / |
Applications:
Thanks to it’s insoluble properties in water and other common solvents,PVPP is widely acted as stabilizers & clarifier for Beer/Wine and other beverages products,it can romove polyphenols and tannins substances during the Beer/Wine/Beverage processing.
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