L-Carnosine

L-carnosine is a small molecule dipeptide composed of two amino acids β-alanine and L-histidine. It is widely found in skeletal muscle, heart, brain and other nerve tissues in the body. A natural antioxidant. Potential antioxidant and anti-glycosylation activity; prevent non-enzymatic glycosylation and protein coupling induced by acetoldehyde.

Product Name: L-carnosine
INCI Name: L-carnosine
CAS NO.: 305-84-0
Synonyms: Carnosine

Product Detail

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product detail

L-Carnosine is a dipeptide comprising beta-alanine and histidine. It is found in muscular and other tissues. It has strong oxidant property as it can scavenge both reactive oxygen species (ROS) and reactive nitrogen species (RNS). Carnosine acts as a cytosolic buffering agent and as a regulator of macrophage function. Attributing to its ability to form complexes with transition metals, it is used to regulate the content of transition metal ions in biological fluids and tissues. Carnosine can prevent aging and can be used to prevent or treat complications of diabetes such as nerve damage, eye disorders (cataracts), and kidney problems.

Key Technical Parameters:

Appearance	White to almost white powder
Optical rotation [α]_D²⁰	+20.0^o~+22.0 ^o (C=2, H₂O)
Heavy metals(Pb)	≤10ppm
Loss on drying	≤1.0%
L-Histidine	≤1.0%
β-Alanine	≤0.1%
Assay	≥99.0%
pH	7.5~8.5

Functions:

L-Carnosine can increase the Hayflick limit in human fibroblasts,as well as appearing to reduce the telomere shortening rate. Carnosine is also considered as a geroprotector.
L-Carnosine is the most effective anti-carbonylation agent yet discovered. (Carbonylation is a pathological step in the age- related degradation of the body proteins. )Carnosine helps to prevent skin collagen cross-linking which leads to loss of elasticity and wrinkles.
L-Carnosine powder also acts as a regulator of zinc and copper concentrations in nerve cells, helping to prevent overstimulation by these neuroactive in the body substantiates.
L-Carnosine is a Super Anti-Oxidant that quenches even the most destructive free radicals: The hydroxyl and the peroxyl radicals, superoxide, and singlet oxygen. Carnosine helps to chelate ionic metals(flush toxins from the body).

Applications:

1. New food additives. In meat processing, carnosine can inhibit fat oxidation and protect meat color. Carnosine and phytic acid resist beef oxidation.
2. The use in cosmetics can prevent skin aging and skin whitening. Carnosine can prevent free radicals generated by smoking, and this free radical can damage the skin more than sunlight. Free radicals are in the body. A very active atom or group of atoms can oxidize other substances in the human body.
3. Oral medicine used in medicine and surgical treatment.