Polyquaternium-1
Polyquaternium-1,also named as Polidronium Chloride,PQ-1,is a detergent-type preservative derived from BAK.It’s formulated in the mid of 1980s by Alcon as a preservative for contact lens storage solutions.Nowadays,it is being increasingly used as a presverative in ophthalmic drops for glaucoma, artificial tear solutions and top cosmetic formuations.
Key Technical Parameters:
(1) 95~100% Powder:
| Appearance | Amber to dark brown solid |
| Odor | Without Stimulation |
| Water solubility | Full Soluble |
| Free Amine | ＜5.0% |
| pH | 6.0~9.0 |
| Chloride | ＜30% |
| Internal standard content | ≥95% |
| Total Number of Aerobic Microbial Count(TAMC) cfu/g | ＜10³ cfu/g |
| Total Yeasts and Molds Count(TYMC) cfu/g | ＜10² cfu/g |
(2) 40% liquid :
| Appearance | Light yellow liquid |
| Odor | Without Stimulation |
| Molecular Weight | 30,000~40,000 |
| Solid Content | ≥33% |
| Chloride | £10% |
| Free Amin | ≤2.0% |
| pH | 6~9 |
| Water Solubility | 100% Soluble |
| Total Aerobic Microbial Count(TAMC) | £1000cfu/g |
| Total Yeasts and Molds Count(TYMC) | £100 cfg/g |
Applications:
Polyquaternium-1is an antimicrobial preservative, with higher antimicrobial effects and lower ocular irritation.used as bactericide in eye drops,soft lenses product and other ophalmic care products formulation.In skin care formulations,it can help to avoid or reduce the allergy and infection possibility.
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