I-L-Glutathione Oxidized

I-L-Glutathione Oxidized (GSSG) ingeyokuvutshelwa kwe-microbial ukuze kutholakale imvubelo ecebile ye-L-Glutathione, bese itholwa i-GSSG ngokuhlukaniswa nokuhlanza kobuchwepheshe besimanje. Isekelwe kabanzi ezintweni eziphilayo, ikakhulukazi idlala indima yokunciphisa ukudluliswa kwe-electron yokunciphisa i-oxidation. Ingavikela amangqamuzana egazi abomvu egazini emonakalweni we-oxidative, ukugcinwa kwe-hemoglobin ku-cysteine esesimweni esincishisiwe.

Igama Lomkhiqizo: I-L-Glutathione Oxidized
Ikhodi Yomkhiqizo: I-YNR-LGO
INCI Igama: I-L-Glutathione Oxidized
Inombolo ye-CAS: 27025-41-8
Omqondofana: I-Glutathione disulfide;I-glutathione (ifomu eline-oxidized); GSSG,Glutathiol;Oxyglutatione
Isisindo se-Molecular: 612.631

Xhumana nathi

Imininingwane Yomkhiqizo

Kungani Khetha i-YR Chemspec

imininingwane yomkhiqizo

I-L-Glutathione Oxidized iyi-peptide eyenziwe ngokwemvelo kumaseli omuntu, akhiwa i-glutamate, i-cysteine ne-glycine. I-glutathione ene-oxidized (GSSG) iwuhlobo lwe-glutathione, olulungiswa ngokufakwa kwe-glutathione encishisiwe nge-hydrogen peroxide ngaphansi kwezimo ze-alkali. Incibilika emanzini, ayincibiliki ku-ethanol. Ingasetshenziselwa ucwaningo lwesayensi nokuhlola. Kuyi-hydrogen receptor yokuzimisela kwe-enzymatic ye-NADP ne-NADPH.

Imisebenzi:

1.I-L-Glutathione Oxidized/I-glutathione ene-oxidized iyi-tripeptide equkethe ukuxhumana okungajwayelekile kwe-peptide phakathi kweqembu le-amine le-cysteine (elixhunywe ukuxhumana kwe-peptide evamile ne-glycine) kanye neqembu le-carboxyl le-glutamate side-chain. I-antioxidant, evimbela ukulimala ezingxenyeni ezibalulekile zamangqamuzana ezibangelwa izinhlobo ze-oksijini ezisebenzayo njengama-radicals mahhala nama-peroxides.

2.I-L-Glutathione Oxidized/Oxidized glutathione are reduceing agents, ekhona ekuhlanganiseni cishe kwe-5 mM kumaseli ezilwane.I-glutathione inciphisa izibopho ze-disulfide ezakhiwe ngaphakathi kwamaprotheni e-cytoplasmic zibe ama-cysteines ngokusebenza njengomnikezeli we-electron.Kule nqubo, i-glutathione iguqulelwa kufomu layo le-oxidized disulfidethi (SG) ebizwa ngokuthi i-glutathione. L(-)-Glutathione.

3.I-L-Glutathione glutathione Oxidized/Oxidized glutathione itholakala cishe kuphela efomini layo elincishisiwe, njengoba i-enzyme eyibuyisela esimweni sayo se-oxidized, i-glutathione reductase, iyasebenza futhi iyakwazi ukucindezela phezu kwengcindezi ye-oxidative.