I-Xanthohumol

  • Xanthohumol

    I-Xanthohumol

    I-Xanthohumol (XN) iyi-flavonoid. Okwamanje itholakala kuma-hops kuphela. Okuqukethwe kwe-Xanthohumol ku-hops kungu-0.1% kuya ku-1%. I-Xanthohumol inyibilika kancane emanzini, futhi inyibilika kalula ku-ethanol. Inemisebenzi eyahlukene yemithi. Isetshenziswa kakhulu ezimbonini zezokwelapha nezokunakekelwa kwezempilo. Ngaleso sikhathi, i-Xanthohumol ingavimbela ukukhiqizwa kwe-melanin okubangelwa i-xanthine ngokuvimbela ukuvezwa kwe-tyrosinase nama-enzyme ahlobene. Izinga layo lokuqedwa kwama-radicals angenawo umoya-mpilo emzimbeni liphakeme izikhathi eziningana kunamanye ama-antioxidants; umsebenzi wayo we-antioxidant unamandla kune-VE, izikhathi ezingama-200 zinamandla kune-resveratrol. Ingasusa ngempumelelo ama-radicals mahhala emzimbeni womuntu. I-Xanthohumol ivimbela umsebenzi we-cyclooxygenase ne-lipoxygenase; ibulala amagciwane agulayo, amagciwane kanye nesikhunta, futhi idambise inkinga yezinduna zesikhumba. Ngakho-ke, i-Xanthohumol ikhombisa ukusetshenziswa okuzokwenzeka emakethe yezimonyo. I-Y&R ithuthukisa u-5% we-Xanthohumol okuyibanga lezimonyo.