Trifluoroacetyl Tripeptide-2(Trifluoroacetyltripeptide-2) /Progeline ni tripeptide ikora ikomoka kuri elastase inhibitor. Irashobora kugabanya synthesis ya proteine ​​ishaje imburagihe, igahindura kuruhuka kwuruhu, kugabanuka no kubyimba biterwa nayo, kunoza uruhu, gukomera no kunoza isura. amakuru yumutekano.

Peptide ni urunigi rwa aside amine ihujwe na peptide. Peptide igira uruhare runini mugutunganya poroteyine, angiogenezi, gukwirakwiza selile, melanogenezesi, kwimuka kwa selile no gutwika. Mu myaka mike ishize, peptide ya bioactive yakoreshejwe cyane mu nganda zo kwisiga. Peptide igomba kuba ifite uburemere buke bwa molekile (Tripeptide -2 ni tripeptide ya syntetique yakozwe nka matrix metalloproteinase na inhibitor ya elastase. Muri vitro ubushakashatsi bwakozwe kugirango harebwe ingaruka za TrifluoroacetylTripeptide -2 kuburinzi bwa ECM, synthesis ya proteoglycan mubikorwa bya selile-matrix, hamwe na progerin synthesis muri fibroblast isanzwe yumuntu ikuze. Iyi poroteyine iherutse kumenyekana Nkumusemburo usanzwe wa senescence. Ibisubizo byerekana ko Trifluoroacetyl Tripeptide-2 ifite intera nini yo kurwanya gusaza. Irashobora kugabanya synthesis ya presenilin, kongera umusaruro wa proteoglycans no kugabanya kolagen, bityo irashobora kugabanya iminkanyari no kongera ubukana bwimitsi. Byongeye kandi, ingaruka zacyo zo kurwanya inkari, kurwanya-kugabanuka no gukomeretsa uruhu zasuzumwe muri ebyiri mu bushakashatsi bwakozwe na vitro. Nk’uko ubushakashatsi bubyerekana, Trifluoroacetyl Tripeptide-2 igira ingaruka buhoro buhoro ku minkanyari, gukomera, gukomera no kugabanuka.

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Imikorere

1. Trifluoroacetyl Tripeptide-2 / Progeline igabanya synthesis ya progerin, MMP na elastase inhibitor, ikongera syndecan, amasezerano ya kolagen kugirango agabanye ibimenyetso byubusaza harimo kugabanuka no gukuna.

2. Trifluoroacetyl Tripeptide-2 / Progeline kugeza kurwego rwakagari kugirango utinde senescence.

3. Trifluoroacetyl Tripeptide-2 / Progeline yongera umusaruro wa kolagen kandi ikabuza ibikorwa byimisemburo ya degradation (kolagenase, elastase, MMP-1, MMP-3, MMP-9).

4. Trifluoroacetyl Tripeptide-2 / Progeline ishoboye gufasha kongera umusaruro wa kolagen, kugabanya isura yiminkanyari, no kugabanya isura yo kugabanuka.

Gusaba

Trifluoroacetyl Tripeptide-2 / Progeline /Peptide Progeline ikora mukubyutsa umusaruro wa sirtuin nibikorwa kugirango wongere igihe cyo kubaho. Iyo ushyizwe kuruhu, worohereza impagarara zo mumaso, biganisha kugabanuka kumirongo yo mumaso hamwe niminkanyari iyo ikoreshejwe nkuko byateganijwe. bizagabanya impagarara zo mumaso no kugenda muguhagarika imitsi yo mumaso. irashobora gukoreshwa mugukora serumu zitandukanye, cream, masike na geles.

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