I-Centella asiatica yeyentsapho ye-Apiaceae kwaye isityalo esihlala ixesha elide. Sisityalo saseTshayina esisetyenziswa kumazwe amaninzi aseAsia ngeenjongo zonyango, ukutya kunye nezithambiso. I-Centella asiatica iqulethe iikhemikhali ezityebileyo kakhulu. Izithako zayo eziphambili ezisebenzayo zezi: i-triterpene saponins (i-saponins ye-triterpene yenziwe ngokuxinwa kwe-triterpene saponins kunye neqela elinye okanye ngaphezulu kweswekile kunye / okanye amanye amaqela ekhemikhali. , i-baicalein, i-fisetin, i-vitexin, i-oyile eguqukayo efana ne-caryophyllene kunye ne-longifolene kunye ne-method Niols, i-polyacetylenic alkenes.

Isenzo kunye nomatshini: ICentella asiatica kunye neemveliso zayo ezikhutshiweyo zine-anti-inflammatory, ukulungisa umonakalo,antioxidant,anti-ukuguga, ukuphuculwa kwe-skin barrier hydration, anti-scar, njl.

1. I-Anti-inflammation: Isicatshulwa se-Centella asiatica sinempembelelo ethile yokuthintela kwiimpendulo ezivuthayo, ngoko ke inefuthe elithile lonyango kwi-atopic dermatitis kunye nezinye izifo ezinxulumene nokuphendula okuvuthayo. Umphumo wokuchasana nokuvuvukala we-Centella asiatica uhambelana nokulawulwa kwayo kwe-cell gene expression kunye nefuthe layo ekukhululweni kwee-cytokines ezinxulumene nazo.

2. Ukulungisa: I-triterpene saponins yaseCentella asiatica inefuthe lokukhuthaza ukuphulukiswa kwesilonda. Njengenye yezinto eziphambili ezisebenzayo kwi-Centella asiatica ukunyanga ukutshisa kunye ne-scalds, i-madecassic acid hydroxyasiatica ingaba nendlela yokusebenza ehambelana nokuvimbela i-lipid peroxidation kunye nokukhuthaza i-Collagen synthesis ihambelana nokuvinjelwa kwe-apoptosis; i-asiaticoside inokukhuthaza ukuphulukiswa kwesilonda ngokunyusa ukubonakaliswa kwe-cyclin BI (i-cyclin BI) i-proliferating cell nuclear antigen PCNA kunye nokuvimbela ukuthuthwa kwenyukliya kweprotheni ye-p65, i-subunit ephambili ye-NF-KB, ukuvimbela ukuvuvukala. Ukugqithiswa kokusabela. Ukongeza, i-hydrogel elungiselelwe kwisicatshulwa seCentella asiatica kunye nezithako zayo ezisebenzayo zinefuthe elihle lokuphilisa kwaye akukho tyhefu ecacileyo yesikhumba.

3. I-Anti-oxidation kunyeanti-ukuguga . I-Centella asiatica extract inamandla okulwa ne-antioxidant kwaye ingaba yinto efanelekileyo kwi-anti-skin aging agents. , i-50% ye-ethanol extract ye-Centella asiatica inokuthintela umonakalo we-oxidative kunye nokufa kweeseli, ukunciphisa umonakalo we-oxidative kwesikhumba, kunye nokulibazisa ukuguga kwesikhumba ngokunyusa umsebenzi we-enzyme ye-antioxidant kunye nokukhuthaza i-fibroblasts ukuphelisa iintlobo ze-oxygen esebenzayo (ROS).

4. Ukuphucula umqobo we-skin barrier hydration. Ukongeza kwiipropathi zayo ezichasayo kunye nokuguga,Isicatshulwa seGotu kola ingasetyenziselwa ukuphucula isithintelo se-skin hydration. I-Centella asiatica, esinye sezithako eziphambili ezisebenzayo kwi-Centella asiatica, inokuphucula ukumanzi kwesikhumba.