I-N-Acetyl-L-carnosine, nomaI-N-Acetylcarnosine(isifinyezo i-NAC) yi-ai-dipeptide . Ifana ne-carnosine kodwa imelana kakhulu nokuwohloka kwe-carnosinase ngenxa yokwengezwa kweqembu le-acetyl.

I-Carnosine(I-L-Carnosine), igama lesayensi elithi β-alanyl-L-histidine, ngu-ai-dipeptideeyakhiwe nge-β-alanine ne-L-histidine, okuqinile okuyikristalu.I-Carnosine akuwona nje umsoco, kodwa futhi angakhuthaza i-cell metabolism futhi abambezele ukuguga. I-Carnosine ingabamba ama-radicals mahhala futhi ivimbele ukusabela kwe-glycosylation. Ine-anti-oxidation kanye nemiphumela ye-anti-glycation. Ingasetshenziswa ngezithako ezimhlophe ukuze kuthuthukiswe umphumela wayo wokuba mhlophe.

I-N-Acetyl-L-carnosine/N-acetyl L-carnosine yabelana ngesakhiwo esifanayo ne-l-carnosine ngokungezwa kweqembu le-acetyl. Kunzima kakhulu kuma-enzyme e-carnosinase ukudiliza lolu hlobo lwe-acylated ye-l-carnosine. I-L-carnosine i-molecule ye-dipeptide eyenzeka ngokwemvelo ehlanganiswe ku-amino acid i-histidine ne-alanine nge-carnosine synthetase enzymes. Kuyi-antioxidant enezici ze-antiglycation ezithuthukisa impilo ende.

Imisipha ingagcina i-carnosine ngenani eliphezulu njengoba umzimba ungayisebenzisi ukwenza amaprotheni. Ukugxila okuphezulu kakhulu kukhona ezingxenyeni zomzimba ezidinga inani elikhulu lamandla, njengemisipha yamathambo, imisipha yenhliziyo, izicubu zezinzwa, nobuchopho.

I-Carnosine ithola igama layo egameni elithi carn, elisho inyama noma inyama. Njengoba igama lisho, i-carnosine ikhona enyameni kuphela. Umzimba ungahlanganisa i-l-carnosine esibindini, kodwa abadla imifino kanye nezilwane ngokuvamile banamazinga aphansi e-carnosine kunabantu abadla inyama. Abantu ngabanye bathatha i-N-acetyl l-carnosine kanye ne-l-carnosine ukuze bakwazi ukuqothula izinhlobo zomoya-mpilo osebenzayo (ama-radicals wamahhala) nokuvikela izingxenye zesakhiwo samangqamuzana ekucindezelekeni kwe-oxidative.

Imingcele Yezobuchwepheshe Ebalulekile

Umsebenzi

I-1.N-Acetyl carnosine ingakhuphula amandla emisipha nokukhuthazela.
2. I-N-Acetyl carnosine canVikela ekulimaleni kwemisebe.
3.N-Acetyl carnosine can Ithuthukisa ukusebenza kwenhliziyo.
4.N-Acetyl carnosine can Isheshisa ukuphola kwesilonda.
I-5.N-Acetyl carnosine ine-Super antioxidant ecisha ngisho nama-radicals amahhala abhubhisa kakhulu.
6.N-Acetyl carnosine can Boost amasosha omzimba futhi kunciphisa ukuvuvukala.
I-7.N-Acetyl carnosine ingasiza ukuchela izinsimbi ezithile ezinzima ezivela emzimbeni (i-chelate isho ukukhipha).
I-8.N-Acetyl carnosine ingase isize izingane ezine-autism.
I-9.N-Acetyl carnosine ingase ikhiqize imiphumela yokulwa nomdlavuza emzimbeni.
I-10.N-Acetyl carnosine ingavikela inqubo yokuguga yobuchopho ngokunciphisa i-lipid peroxidation kanye nokusimamisa ulwelwesi lwamaseli.

Isicelo

1.Izithasiselo zokudla ezintsha;
I-2.N-Acetyl carnosine iyinhlanganisela ye-β-alanine ne-histidine dipeptide, ingahlanganiswa ezilwaneni;
3.N-Acetyl carnosine ekucutshungulweni kwenyama ukuvimbela i-oxidation yamafutha futhi ivikele indima yenyama;
I-4.N-Acetyl carnosine ingavimbela ukuguga kwesikhumba kanye nomphumela wokuba mhlophe kwesikhumba;
I-5.N-Acetyl carnosine njengempahla eluhlaza kuma-antioxidant ekwelapheni ulwelwesi oludala;
I-6.N-Acetyl carnosine ingakhuthaza ukuphulukiswa kwesilonda

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