Ama-Ceramides ayizithako zokunakekelwa kwesikhumba ezidonse ukunaka okusabalele embonini yezimonyo. Amabili kulawa ma-ceramides, i-Ceramide NP ne-Ceramide AP, aziwa ngezakhiwo zawo eziphawulekayo ekulungiseni isikhumba nasekukhanyiseni. I-Ceramide AP yaziwa ngamakhono ayo okulungisa isikhumba, kuyilapho i-Ceramide NP iphumelela kakhulu ekukhanyiseni ibala. Lezi zithako zezimonyo seziphenduke ukukhetha okudumile emikhiqizweni eminingi yokunakekelwa kwesikhumba, enikeza uhla lwezinzuzo kubantu abafuna ukuthuthukisa impilo nokubukeka kwesikhumba sabo.

I-Ceramide AP ingumdlali omkhulu embonini yezimonyo, eyaziwa ngezakhiwo zayo ezimangalisayo zokulungisa isikhumba. Le ceramide isebenza ngokugcwalisa ama-lipids emvelo kusithiyo sesikhumba ukusiza ukuqinisa nokuvikela isikhumba kuma-stresses emvelo. Lapho isikhumba silimele noma sonakalisiwe, i-Ceramide AP iyangena ukuze isize enqubweni yokulungisa futhi ibuyisele amazinga omswakama esikhumba. Ngokuhlanganisa imikhiqizo equkethe i-Ceramide AP ohlelweni lwabo lokunakekelwa kwesikhumba, abantu bangathola ukuthuthuka okumangazayo ekuthunjweni kwesikhumba nokubukeka kwayo yonke.

I-Ceramide NP, ngakolunye uhlangothi, idumile ngenxa yekhono layo lokukhanyisa ibala. Le ceramide isebenza ngokuvimbela ukukhiqizwa kwe-melanin, i-pigment ebangela umbala wesikhumba. Ngokwenza kanjalo, i-Ceramide NP isiza ukunciphisa ukubukeka kwamabala amnyama, i-hyperpigmentation kanye nethoni yesikhumba engalingani. Ukusetshenziswa njalo kwemikhiqizo yokunakekelwa kwesikhumba equkethe i-Ceramide NP kungaholela ebaleni elikhazimulayo, elilinganayo, elingathuthukisa ukuzethemba komuntu siqu nokubukeka okunempilo.

Imboni yezimonyo yasheshe yaqaphela amandla alawa maceramide futhi yawahlanganisa emikhiqizweni ehlukahlukene yokunakekelwa kwesikhumba. Imikhiqizo equkethe i-Ceramide AP ne-Ceramide NP isukela ezintweni ezithambisayo nama-serum kuye kwezihlanza namamaski. Abantu bangakhetha ohlwini lwezinketho ezifanelana nezidingo zabo ezithile zokunakekelwa kwesikhumba, noma ngabe ukulungisa isikhumba esonakele, ukukhanyisa ibala, noma inhlanganisela yakho kokubili. Lezi zithako eziqanjiwe ziguqule imboni yezimonyo, zanikeza izixazululo ezisebenzayo ezinkingeni zabathengi zokunakekelwa kwesikhumba.

Abantu abaningi ngokwengeziwe baphendukela emikhiqizweni equkethe ama-ceramides, njenge-Ceramide AP ne-Ceramide NP, ngenxa yokusebenza kwayo okumangalisayo. Ezweni lapho ukunakekelwa kwesikhumba kubalulekile, abantu bafuna izixazululo ezisebenzayo zezidingo zabo ezihlukile. Amandla e-ceramides asemandleni abo okondla nokuqinisa isikhumba kusuka ngaphakathi, ukukhuthaza ibala elinempilo nelinempilo. Njengoba ucwaningo luqhubeka nokuveza amandla alezi zithako, imboni yezimonyo iqinisekile ukuthi izofakaza intuthuko ekwakhiweni kokunakekelwa kwesikhumba.

Sengiphetha, i-Ceramide AP ne-Ceramide NP zingabashintshi begeyimu embonini yezimonyo ezisebenza kahle kakhuluukulungiswa kwesikhumbafuthiukwenza mhlophe . Lezi zithako zisetshenziswe emikhiqizweni eminingi yokunakekelwa kwesikhumba ukuze abantu bakwazi ukuthola isikhumba esinempilo, esicwebezelayo. Kungakhathaliseki ukuthi ukulungisa isikhumba esonakele noma ukukhanyisa ibala, ama-ceramides afana ne-AP ne-NP anganikeza izixazululo ezisebenzayo. Njengoba ukuthandwa kwalezi zithako kuqhubeka kudlondlobala, kuyacaca ukuthi zizohlala lapha, zibumba ikusasa lemboni yezimonyo futhi zishintsha indlela esinakekela ngayo isikhumba sethu.