I-Bear fruit, njengoba negama lisho, isithelo esithela uthando lokudla, eyaziwa nangokuthi amagilebhisi ebhere. Amajikijolo asatshalaliswa kabanzi ezindaweni eziphansi eNyakatho Nenkabazwe. I-Arbutin, eyaziwa nangokuthi i-arbutin, iyikristalu emhlophe efana nenaliti noma impushana ekhishwa emaqabunga esithelo sebhere. Amaqabunga e-bearberry aqukethe i-arbutin, okwamanje eyisithako esimhlophe esiphephile nesisebenzayo. I-Arbutin ihlukaniswe yaba izinhlobo ezimbili: i-Alpha arbutin ne-Beta arbutin. Indlela ye-chemical synthesis ye-arbutin okwamanje iyindlela eyinhloko yokulungiselela i-arbutin. Inezinzuzo zekhwalithi enhle yokuhlanganisa kanye nezindleko eziphansi zokukhiqiza. Emakethe yezimonyo, i-arbutin isetshenziswa kabanzi. I-Arbutin incibilika kalula emanzini ashisayo, i-methanol, i-ethanol, nezixazululo ezinamanzi ze-propylene glycol ne-glycerol, kodwa ayincibiliki ezincibilikisini ezifana ne-ether, i-chloroform, ne-petroleum ether.

I-Arbutinayifakiwe kuphela kumafomula weimikhiqizo emhlophe, kodwa futhi iba yi-antioxidantisithako esisebenzayo emikhiqizweni eminingi yokunakekelwa kwesikhumba. Akukho ukushoda kwezinto zokuhlanza ubuso, imaski yobuso, izinto zokuthambisa, okhilimu neminye imikhiqizo yobuhle nokunakekelwa kwesikhumba ene-arbutin emakethe. Ngokwezibalo zemakethe, ukusetshenziswa kwe-arbutin kwezimonyo kukhula unyaka nonyaka.

Imisebenzi esemqoka ye-arbutin yile:

1. Umphumela wokuba mhlophe. Okokuqala, kufanele siqonde indlela yokuphila kokumnyama kwesikhumba. Isici esiyinhloko esibangela ukujula kombala wesikhumba okuqukethwe nokusatshalaliswa kwe-melanin esikhumbeni, ekhiqizwa ngama-melanocyte kungqimba oluyisisekelo lwe-epidermis yesikhumba. I-Tyrosine, into yokuqala esetshenziselwa ukwakhiwa kwe-melanin, ibhekana nochungechunge lwezinqubo eziyinkimbinkimbi ze-biochemical ngaphansi kwesenzo se-tyrosinase, ekugcineni yakha i-melanin, edluliselwa kusuka ngaphakathi ngaphandle ngokusebenzisa ungqimba oluyisisekelo lwesikhumba kuya oqweqweni olungaphandle lwe-epidermis. , ukufaka umbala esikhumbeni nokwenza amabala. I-Arbutin ingangena ngokushesha esikhumbeni futhi ingavimbela ngempumelelo umsebenzi we-tyrosinase esikhumbeni futhi ivimbele ukwakheka kwe-melanin ngokuhlanganisa ngokuqondile ne-tyrosinase ngaphakathi kwebanga lokuhlushwa elingenabo ubuthi kuma-melanocyte. Ngasikhathi sinye, i-arbutin ingasheshisa ukubola nokuphuma kwe-melanin, inciphise ukugqama kwesikhumba, isuse amabala namabala. Kuyinto ephephile futhi ephumelelayoukwenza mhlophe impahla eluhlazaesetshenziswa kakhulu namuhla.

2. Gcoba ama-radicals mahhala. I-Arbutin ingasusa ama-radicals mahhala kumetabolism yesikhumba, ivikele isikhumba emonakalweni, ihlambulule i-melanin eyakhiwe, isheshise ukubola nokuphuma kwe-melanin, inciphise ukugqama kwesikhumba, futhi isuse amabala namafreckles.