I-Xanthohumol(XN) i-flavonoid efakwe ngaphambili etholakala ngokwemvelo esitshalweni se-flowering hop (Humulus lupulus) esivame ukusetshenziselwa ukwenza isiphuzo esidakayo esaziwa ngokuthi ubhiya.I-Xanthohumol ingenye yezakhi eziyinhloko ze-Humulus lupulus. I-Xanthohumol kubikwe ukuthi inempahla yokudambisa, umphumela we-Antiinvasive, umsebenzi we-estrogenic, i-bioactivities ehlobene nomdlavuza, umsebenzi we-antioxidant, umphumela wesisu, imiphumela ye-antibacterial kanye ne-antifungal ezifundweni zakamuva.

Amapharamitha Abalulekile Wezobuchwepheshe:

Umthombo we-Xanthohumol:

AmaHops (igama lesiLatini: Hunulus lupulus Linn.) izimbali ezomisiwe ezivuthiwe ze-moraceae plant hop. Zingenye yezinto ezisetshenziswa kakhulu zokukhiqiza ubhiya. Banganikeza ubhiya ngephunga eliyingqayizivele nokubaba kanye nomphumela we-antiseptic. Amahops asakazwa kakhulu phakathi kuka-35°-55° enyakatho naseningizimu yenkabazwe. Lesi sitshalo sivela eYurophu, eMelika nase-Asia. Kunamahops asendle enyakatho yeSinkiang, kanye nokutshalwa kokwenziwa enyakatho-mpumalanga nasenyakatho yeChina. Ama-Hops nawo awuhlobo lwesitshalo se-homologous somuthi futhi esidliwayo esinomlando omude wokusetshenziswa. Zisetshenziswa kakhulu njengesinongo, isinongo, futhi zingasetshenziselwa ukwenza itiye. Abantu basebenzisa i-inflorescence yesifazane yama-hops njengomuthi, ongathuthukisa ukugaya, usize i-diuresis, futhi ukhulule ukukhathazeka. Lesi sitshalo sicebile nge-hop resin, uwoyela we-hop, ama-polyphenols, ama-flavonoid nezinye izithako zokwelapha. Ine-antibacterial, sedative, kanye neminye imisebenzi ye-pharmacological yokwelapha isifo sofuba, i-neurasthenia, uchoko. Inenani elikhulu embonini yezokwelapha nezempilo.

Izicelo:

• I-Xanthohumol ingaba yi-antibacterial kanye ne-anti-inflammatory, ngakho-ke ingasetshenziswa ukwelapha izinduna nezinye izifo zobuso.
• I-Xanthohumol inomphumela oqinile wokuvimbela emsebenzini we-tyrosinase. Ingasetshenziswa emikhiqizweni yokunakekela isikhumba eyenza ibe mhlophe.
• I-Xanthohumol iyi-antioxidant engasetshenziswa esikhumbeni selanga ukunciphisa ukulimala kwe-UV esikhumbeni.
• I-Xanthohumol inezakhiwo ezibalulekile ze-anticancer ukuvimbela umdlavuza wesikhumba.

Izinzuzo:

I-Anti-oxidation

Ososayensi baseJalimane bakhombisile ukuthi i-Xanthohumol ingakhipha umoya-mpilo wama-radicals mahhala emzimbeni. Iphindwe izikhathi eziningana kunamanye ama-antioxidants. I-anti-oxidative kakhulu kune-VE futhi inamandla izikhathi ezingu-200 kune-resveratrol. Ingenye ye-antioxidant enamandla kakhulu eyaziwayo. Ingasusa ngempumelelo ama-radicals mahhala ayingozi emzimbeni womuntu futhi ibambezele ukuguga kwesikhumba. Imiphumela yokuhlolwa ikhombisa ukuthi i-antioxidant ye-Xanthohumol ingathuthukiswa uma ihlanganiswa ne-citric acid, i-sodium citrate kanye novithamini C.

Isikhumba esimhlophe

I-Xanthohumol ivimbela ukubonakaliswa kwe-tyrosinase nama-enzyme ahlobene ukumisa ukwakheka kwe-melanin okubangelwa i-xanthine. Ngaleyo ndlela kungaba nomphumela wokwenza isikhumba sibe mhlophe.

I-Anti-bacterial kanye ne-anti-inflammation

I-Xanthohumol ingavimbela umsebenzi we-cyclooxygenase ne-lipoxygenase, ngakho-ke inomphumela we-antibacterial and anti-inflammatory. Ingabulala amagciwane, amagciwane kanye nesikhunta. Ucwaningo luye lwaphakamisa ukuthi i-Xanthohumol ne-isoxanthohumol ingalwa ne-cytomegalovirus, i-herpes HSV-1 ne-HSV-2 virus. Futhi umphumela we-Xanthohumol unamandla kakhulu kunalowo we-isoxanthohumol. Ingadambisa inkinga yezinduna zesikhumba.

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