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Ergothioneine

Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.
  • Product Name Ergothioneine
  • Product Code YNR-EGT
  • Synonyms L-Ergothioneine,EGT
  • INCI Name Ergothioneine
  • CAS No. 497-30-3

Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.

EGT is accumulated into different cellular compartments via its specific transporter OCTN-1,abundantly expressed in mitochondrial DNA is especially vulnerable to stress because unlike nuclear DNA,there are no histones to protect mitochondrial DNA.Reactive oxygen species,like superoxides O2- generated in the mitochondria by respiration,are directly scavenged by EGT.EGT presents in the cytoplasm also scavenges a variety of ROS and reactive nitrogen species.EGT absorbs UV radiation and prevents DNA breaks and mutations.

Key Technical Parameters

Appearance White Powder
Assay 99% min.
Loss on Drying 1% max.
Heavy Metals(as Pb) 10 ppm max.
Arsenic 2 ppm max.
Lead 2 ppm max.
Mercury 1 ppm max.
E.Coli Negative
Total Plate Count 1,000 cfu/g max.
Yeast and Mold 100 cfu/g max.

Applications:

Anti-Aging products,sun care products,antioxidant products,skin protection,skin regeneration.

Recommended Dosage:0.5~2%

 


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